{"id":91786,"date":"2025-06-01T11:05:38","date_gmt":"2025-06-01T11:05:38","guid":{"rendered":"https:\/\/exam.pscnotes.com\/mcq\/?p=91786"},"modified":"2025-06-01T11:05:38","modified_gmt":"2025-06-01T11:05:38","slug":"in-the-context-of-recent-advances-in-human-reproductive-technology-p","status":"publish","type":"post","link":"https:\/\/exam.pscnotes.com\/mcq\/in-the-context-of-recent-advances-in-human-reproductive-technology-p\/","title":{"rendered":"In the context of recent advances in human reproductive technology, \u201cP"},"content":{"rendered":"

In the context of recent advances in human reproductive technology, \u201cPronuclear Transfer\u201d is used for<\/p>\n

[amp_mcq option1=”fertilization of egg in vitro by the donor sperm” option2=”genetic modification of sperm producing cells” option3=”development of stem cells into functional embryos” option4=”prevention of mitochondrial diseases in offspring” correct=”option4″]<\/p>\n

\n
\n
This question was previously asked in<\/div>\n
UPSC IAS – 2020<\/div>\n<\/div>\n
Download PDF<\/a>Attempt Online<\/a><\/div>\n<\/div>\n
\nPronuclear Transfer is a technique used in assisted reproductive technology aimed at preventing the transmission of mitochondrial diseases from a mother to her child. It involves transferring the nuclear genetic material (contained in the pronuclei after fertilization) from the intended parents’ fertilized egg into a donor egg that has healthy mitochondria but has had its own nucleus removed. This creates a zygote with the intended parents’ nuclear DNA and the donor’s mitochondrial DNA, which can then be implanted.
\n<\/section>\n
\nPronuclear Transfer is a method specifically designed to prevent the inheritance of mitochondrial diseases.
\n<\/section>\n
\nThis technique is sometimes referred to as ‘three-parent IVF’ because the resulting child effectively has genetic material from three individuals: nuclear DNA from both parents and mitochondrial DNA from a donor. Another related technique is Maternal Spindle Transfer.
\n<\/section>\n","protected":false},"excerpt":{"rendered":"

In the context of recent advances in human reproductive technology, \u201cPronuclear Transfer\u201d is used for [amp_mcq option1=”fertilization of egg in vitro by the donor sperm” option2=”genetic modification of sperm producing cells” option3=”development of stem cells into functional embryos” option4=”prevention of mitochondrial diseases in offspring” correct=”option4″] This question was previously asked in UPSC IAS – 2020 … <\/p>\n

Detailed SolutionIn the context of recent advances in human reproductive technology, \u201cP<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1092],"tags":[1288,1117,1146],"class_list":["post-91786","post","type-post","status-publish","format-standard","hentry","category-upsc-ias","tag-1288","tag-biology","tag-genetic-engineering-and-biotechnology","no-featured-image-padding"],"yoast_head":"\nIn the context of recent advances in human reproductive technology, \u201cP<\/title>\n<meta name=\"description\" content=\"Pronuclear Transfer is a technique used in assisted reproductive technology aimed at preventing the transmission of mitochondrial diseases from a mother to her child. It involves transferring the nuclear genetic material (contained in the pronuclei after fertilization) from the intended parents' fertilized egg into a donor egg that has healthy mitochondria but has had its own nucleus removed. This creates a zygote with the intended parents' nuclear DNA and the donor's mitochondrial DNA, which can then be implanted. 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