\nStatement 1: Genetic changes can be introduced in germline cells (cells that produce eggs or sperm) using gene editing technologies like CRISPR-Cas9. This is technically feasible, meaning the capabilities exist to perform such modifications. However, editing the germline in humans is highly controversial due to ethical concerns regarding heritable changes and is subject to strict regulations or prohibitions in most countries. The statement says “can be introduced”, which is true from a technical standpoint. Correct.
\nStatement 2: A person’s genome can be edited at a very early stage of development, such as the embryonic stage before implantation or shortly after. This is known as embryo editing or pre-implantation genetic modification. Gene editing tools can be applied to correct genetic mutations in embryos. Similar to germline editing, this is technically possible but raises significant ethical debates and regulatory challenges. Correct.
\nStatement 3: Human induced pluripotent stem cells (iPSCs) or human embryonic stem cells can be injected into the embryos of other species, such as pigs or sheep, to create human-animal chimeras. The goal of such research is often to study human development, model diseases, or potentially grow human tissues or organs within the animal host for future transplantation purposes. This is an active area of biomedical research. Correct.
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