{"id":88135,"date":"2025-06-01T07:03:09","date_gmt":"2025-06-01T07:03:09","guid":{"rendered":"https:\/\/exam.pscnotes.com\/mcq\/?p=88135"},"modified":"2025-06-01T07:03:09","modified_gmt":"2025-06-01T07:03:09","slug":"muscle-fatigue-is-due-to-the-accumulation-of","status":"publish","type":"post","link":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/","title":{"rendered":"Muscle fatigue is due to the accumulation of:"},"content":{"rendered":"<p>Muscle fatigue is due to the accumulation of:<\/p>\n<p>[amp_mcq option1=&#8221;Cholesterol&#8221; option2=&#8221;Lactic acid&#8221; option3=&#8221;Lipoic acid&#8221; option4=&#8221;Triglycerides&#8221; correct=&#8221;option2&#8243;]<\/p>\n<div class=\"psc-box-pyq-exam-year-detail\">\n<div class=\"pyq-exam\">\n<div class=\"psc-heading\">This question was previously asked in<\/div>\n<div class=\"psc-title line-ellipsis\">UPSC NDA-2 &#8211; 2015<\/div>\n<\/div>\n<div class=\"pyq-exam-psc-buttons\"><a href=\"\/pyq\/pyq-upsc-nda-2-2015.pdf\" target=\"_blank\" class=\"psc-pdf-button\" rel=\"noopener\">Download PDF<\/a><a href=\"\/pyq-upsc-nda-2-2015\" target=\"_blank\" class=\"psc-attempt-button\" rel=\"noopener\">Attempt Online<\/a><\/div>\n<\/div>\n<section id=\"pyq-correct-answer\">\nMuscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid.<br \/>\n<\/section>\n<section id=\"pyq-key-points\">\nWhen muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.<br \/>\n<\/section>\n<section id=\"pyq-additional-information\">\nWhile other factors like depletion of energy stores (ATP, glycogen), ion imbalances, and central nervous system fatigue also contribute to overall fatigue, lactic acid accumulation is a significant factor in muscle fatigue during anaerobic work. Cholesterol and triglycerides are types of fats, and lipoic acid is an antioxidant coenzyme; none of these are directly responsible for the acute fatigue caused by intense muscle exertion.<br \/>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Muscle fatigue is due to the accumulation of: [amp_mcq option1=&#8221;Cholesterol&#8221; option2=&#8221;Lactic acid&#8221; option3=&#8221;Lipoic acid&#8221; option4=&#8221;Triglycerides&#8221; correct=&#8221;option2&#8243;] This question was previously asked in UPSC NDA-2 &#8211; 2015 Download PDFAttempt Online Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Muscle fatigue is due to the accumulation of:\" class=\"read-more button\" href=\"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/#more-88135\">Detailed Solution<span class=\"screen-reader-text\">Muscle fatigue is due to the accumulation of:<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1094],"tags":[1443,1117,1328],"class_list":["post-88135","post","type-post","status-publish","format-standard","hentry","category-upsc-nda-2","tag-1443","tag-biology","tag-skeletal-and-muscle-system","no-featured-image-padding"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.2 (Yoast SEO v23.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Muscle fatigue is due to the accumulation of:<\/title>\n<meta name=\"description\" content=\"Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Muscle fatigue is due to the accumulation of:\" \/>\n<meta property=\"og:description\" content=\"Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/\" \/>\n<meta property=\"og:site_name\" content=\"MCQ and Quiz for Exams\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-01T07:03:09+00:00\" \/>\n<meta name=\"author\" content=\"rawan239\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"rawan239\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Muscle fatigue is due to the accumulation of:","description":"Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/","og_locale":"en_US","og_type":"article","og_title":"Muscle fatigue is due to the accumulation of:","og_description":"Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.","og_url":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/","og_site_name":"MCQ and Quiz for Exams","article_published_time":"2025-06-01T07:03:09+00:00","author":"rawan239","twitter_card":"summary_large_image","twitter_misc":{"Written by":"rawan239","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/","url":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/","name":"Muscle fatigue is due to the accumulation of:","isPartOf":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#website"},"datePublished":"2025-06-01T07:03:09+00:00","dateModified":"2025-06-01T07:03:09+00:00","author":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/5807dafeb27d2ec82344d6cbd6c3d209"},"description":"Muscle fatigue during strenuous exercise is primarily associated with the accumulation of lactic acid. When muscles undergo intense activity with insufficient oxygen supply (anaerobic respiration), glucose is broken down into pyruvate, which is then converted into lactic acid. The build-up of lactic acid in muscle tissue lowers pH and interferes with muscle contraction mechanisms, leading to a burning sensation and fatigue.","breadcrumb":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/exam.pscnotes.com\/mcq\/muscle-fatigue-is-due-to-the-accumulation-of\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/exam.pscnotes.com\/mcq\/"},{"@type":"ListItem","position":2,"name":"UPSC NDA-2","item":"https:\/\/exam.pscnotes.com\/mcq\/category\/upsc-nda-2\/"},{"@type":"ListItem","position":3,"name":"Muscle fatigue is due to the accumulation of:"}]},{"@type":"WebSite","@id":"https:\/\/exam.pscnotes.com\/mcq\/#website","url":"https:\/\/exam.pscnotes.com\/mcq\/","name":"MCQ and Quiz for Exams","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/exam.pscnotes.com\/mcq\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/5807dafeb27d2ec82344d6cbd6c3d209","name":"rawan239","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/761a7274f9cce048fa5b921221e7934820d74514df93ef195a9d22af0c1c9001?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/761a7274f9cce048fa5b921221e7934820d74514df93ef195a9d22af0c1c9001?s=96&d=mm&r=g","caption":"rawan239"},"sameAs":["https:\/\/exam.pscnotes.com"],"url":"https:\/\/exam.pscnotes.com\/mcq\/author\/rawan239\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts\/88135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/comments?post=88135"}],"version-history":[{"count":0,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts\/88135\/revisions"}],"wp:attachment":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/media?parent=88135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/categories?post=88135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/tags?post=88135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}