{"id":86298,"date":"2025-06-01T03:42:54","date_gmt":"2025-06-01T03:42:54","guid":{"rendered":"https:\/\/exam.pscnotes.com\/mcq\/?p=86298"},"modified":"2025-06-01T03:42:54","modified_gmt":"2025-06-01T03:42:54","slug":"which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph","status":"publish","type":"post","link":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/","title":{"rendered":"Which one of the following pairs of enzymes do not work at acidic pH ?"},"content":{"rendered":"<p>Which one of the following pairs of enzymes do not work at acidic pH ?<\/p>\n<p>[amp_mcq option1=&#8221;Trypsin and Pepsin&#8221; option2=&#8221;Chymotrypsin and Pepsin&#8221; option3=&#8221;Trypsin and Amylase&#8221; option4=&#8221;Pepsin and Amylase&#8221; correct=&#8221;option3&#8243;]<\/p>\n<div class=\"psc-box-pyq-exam-year-detail\">\n<div class=\"pyq-exam\">\n<div class=\"psc-heading\">This question was previously asked in<\/div>\n<div class=\"psc-title line-ellipsis\">UPSC CDS-2 &#8211; 2022<\/div>\n<\/div>\n<div class=\"pyq-exam-psc-buttons\"><a href=\"\/pyq\/pyq-upsc-cds-2-2022.pdf\" target=\"_blank\" class=\"psc-pdf-button\" rel=\"noopener\">Download PDF<\/a><a href=\"\/pyq-upsc-cds-2-2022\" target=\"_blank\" class=\"psc-attempt-button\" rel=\"noopener\">Attempt Online<\/a><\/div>\n<\/div>\n<section id=\"pyq-correct-answer\">\nEnzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment.<br \/>\n<\/section>\n<section id=\"pyq-key-points\">\n&#8211; Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range.<br \/>\n&#8211; Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH.<br \/>\n&#8211; Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH.<br \/>\nThe question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.<br \/>\n<\/section>\n<section id=\"pyq-additional-information\">\nThe pH in different parts of the human digestive system varies significantly. The mouth is near neutral, the stomach is highly acidic, the small intestine is alkaline, and the large intestine is slightly acidic. This variation allows for optimal activity of different digestive enzymes.<br \/>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Which one of the following pairs of enzymes do not work at acidic pH ? [amp_mcq option1=&#8221;Trypsin and Pepsin&#8221; option2=&#8221;Chymotrypsin and Pepsin&#8221; option3=&#8221;Trypsin and Amylase&#8221; option4=&#8221;Pepsin and Amylase&#8221; correct=&#8221;option3&#8243;] This question was previously asked in UPSC CDS-2 &#8211; 2022 Download PDFAttempt Online Enzymes have optimal pH ranges at which they function effectively. Different enzymes in &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Which one of the following pairs of enzymes do not work at acidic pH ?\" class=\"read-more button\" href=\"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/#more-86298\">Detailed Solution<span class=\"screen-reader-text\">Which one of the following pairs of enzymes do not work at acidic pH ?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1088],"tags":[1108,1117,1289],"class_list":["post-86298","post","type-post","status-publish","format-standard","hentry","category-upsc-cds-2","tag-1108","tag-biology","tag-digestive-system","no-featured-image-padding"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.2 (Yoast SEO v23.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Which one of the following pairs of enzymes do not work at acidic pH ?<\/title>\n<meta name=\"description\" content=\"Enzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment. - Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range. - Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH. - Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH. The question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Which one of the following pairs of enzymes do not work at acidic pH ?\" \/>\n<meta property=\"og:description\" content=\"Enzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment. - Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range. - Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH. - Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH. The question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/\" \/>\n<meta property=\"og:site_name\" content=\"MCQ and Quiz for Exams\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-01T03:42:54+00:00\" \/>\n<meta name=\"author\" content=\"rawan239\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"rawan239\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Which one of the following pairs of enzymes do not work at acidic pH ?","description":"Enzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment. - Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range. - Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH. - Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH. The question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/","og_locale":"en_US","og_type":"article","og_title":"Which one of the following pairs of enzymes do not work at acidic pH ?","og_description":"Enzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment. - Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range. - Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH. - Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH. The question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.","og_url":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/","og_site_name":"MCQ and Quiz for Exams","article_published_time":"2025-06-01T03:42:54+00:00","author":"rawan239","twitter_card":"summary_large_image","twitter_misc":{"Written by":"rawan239","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/","url":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/","name":"Which one of the following pairs of enzymes do not work at acidic pH ?","isPartOf":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#website"},"datePublished":"2025-06-01T03:42:54+00:00","dateModified":"2025-06-01T03:42:54+00:00","author":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/5807dafeb27d2ec82344d6cbd6c3d209"},"description":"Enzymes have optimal pH ranges at which they function effectively. Different enzymes in the digestive system operate at different pH levels corresponding to the environment in which they are found. We need to identify the pair of enzymes that do not function in an acidic environment. - Pepsin is a protease found in the stomach, which has a highly acidic pH (around 1.5-2.5) due to the secretion of hydrochloric acid. Pepsin has an optimal pH in this acidic range. - Trypsin and Chymotrypsin are proteases found in the small intestine, where the environment is alkaline (pH around 8) due to the secretion of bicarbonate from the pancreas. They do not work at acidic pH. - Amylase (like salivary amylase and pancreatic amylase) works best at neutral to slightly alkaline pH (around 6.7-7.0 for salivary, around 8 for pancreatic). It is largely inactive at acidic stomach pH. The question asks for the pair of enzymes that *do not* work at acidic pH. Trypsin and Amylase both have optimal pH values in the neutral or alkaline range and are inactive in acidic conditions. Pepsin, however, works at acidic pH.","breadcrumb":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/exam.pscnotes.com\/mcq\/which-one-of-the-following-pairs-of-enzymes-do-not-work-at-acidic-ph\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/exam.pscnotes.com\/mcq\/"},{"@type":"ListItem","position":2,"name":"UPSC CDS-2","item":"https:\/\/exam.pscnotes.com\/mcq\/category\/upsc-cds-2\/"},{"@type":"ListItem","position":3,"name":"Which one of the following pairs of enzymes do not work at acidic pH ?"}]},{"@type":"WebSite","@id":"https:\/\/exam.pscnotes.com\/mcq\/#website","url":"https:\/\/exam.pscnotes.com\/mcq\/","name":"MCQ and Quiz for Exams","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/exam.pscnotes.com\/mcq\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/5807dafeb27d2ec82344d6cbd6c3d209","name":"rawan239","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/761a7274f9cce048fa5b921221e7934820d74514df93ef195a9d22af0c1c9001?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/761a7274f9cce048fa5b921221e7934820d74514df93ef195a9d22af0c1c9001?s=96&d=mm&r=g","caption":"rawan239"},"sameAs":["https:\/\/exam.pscnotes.com"],"url":"https:\/\/exam.pscnotes.com\/mcq\/author\/rawan239\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts\/86298","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/comments?post=86298"}],"version-history":[{"count":0,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/posts\/86298\/revisions"}],"wp:attachment":[{"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/media?parent=86298"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/categories?post=86298"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/exam.pscnotes.com\/mcq\/wp-json\/wp\/v2\/tags?post=86298"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}