{"id":85697,"date":"2025-06-01T03:25:01","date_gmt":"2025-06-01T03:25:01","guid":{"rendered":"https:\/\/exam.pscnotes.com\/mcq\/?p=85697"},"modified":"2025-06-01T03:25:01","modified_gmt":"2025-06-01T03:25:01","slug":"human-insulin-molecule-is-composed-of-one-%ce%b1-chain-having-21-amino-acid","status":"publish","type":"post","link":"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-%ce%b1-chain-having-21-amino-acid\/","title":{"rendered":"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid"},"content":{"rendered":"<p>Human insulin molecule is composed of one \u03b1-chain having 21 amino acids and one \u03b2-chain having 30 amino acids. How many functional insulin genes occur in adult humans?<\/p>\n<p>[amp_mcq option1=&#8221;One&#8221; option2=&#8221;Two&#8221; option3=&#8221;Three&#8221; option4=&#8221;Four&#8221; correct=&#8221;option1&#8243;]<\/p>\n<div class=\"psc-box-pyq-exam-year-detail\">\n<div class=\"pyq-exam\">\n<div class=\"psc-heading\">This question was previously asked in<\/div>\n<div class=\"psc-title line-ellipsis\">UPSC CDS-2 &#8211; 2017<\/div>\n<\/div>\n<div class=\"pyq-exam-psc-buttons\"><a href=\"\/pyq\/pyq-upsc-cds-2-2017.pdf\" target=\"_blank\" class=\"psc-pdf-button\" rel=\"noopener\">Download PDF<\/a><a href=\"\/pyq-upsc-cds-2-2017\" target=\"_blank\" class=\"psc-attempt-button\" rel=\"noopener\">Attempt Online<\/a><\/div>\n<\/div>\n<section id=\"pyq-correct-answer\">\nThere are two functional insulin genes in adult humans.<br \/>\n<\/section>\n<section id=\"pyq-key-points\">\nThe gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. Both copies are typically functional, encoding the proinsulin precursor that is cleaved to form mature insulin.<br \/>\n<\/section>\n<section id=\"pyq-additional-information\">\nMutations in the INS gene can lead to various forms of diabetes, such as Maturity Onset Diabetes of the Young type 1 (MODY1). The structure of the insulin molecule, composed of alpha and beta chains linked by disulfide bonds, is derived from a single proinsulin polypeptide chain.<br \/>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Human insulin molecule is composed of one \u03b1-chain having 21 amino acids and one \u03b2-chain having 30 amino acids. How many functional insulin genes occur in adult humans? [amp_mcq option1=&#8221;One&#8221; option2=&#8221;Two&#8221; option3=&#8221;Three&#8221; option4=&#8221;Four&#8221; correct=&#8221;option1&#8243;] This question was previously asked in UPSC CDS-2 &#8211; 2017 Download PDFAttempt Online There are two functional insulin genes in adult &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid\" class=\"read-more button\" href=\"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-%ce%b1-chain-having-21-amino-acid\/#more-85697\">Detailed Solution<span class=\"screen-reader-text\">Human insulin molecule is composed of one \u03b1-chain having 21 amino acid<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1088],"tags":[1101,1117,1199],"class_list":["post-85697","post","type-post","status-publish","format-standard","hentry","category-upsc-cds-2","tag-1101","tag-biology","tag-heredity","no-featured-image-padding"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.2 (Yoast SEO v23.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Human insulin molecule is composed of one \u03b1-chain having 21 amino acid<\/title>\n<meta name=\"description\" content=\"There are two functional insulin genes in adult humans. The gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. Both copies are typically functional, encoding the proinsulin precursor that is cleaved to form mature insulin.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-\u03b1-chain-having-21-amino-acid\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid\" \/>\n<meta property=\"og:description\" content=\"There are two functional insulin genes in adult humans. The gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. Both copies are typically functional, encoding the proinsulin precursor that is cleaved to form mature insulin.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-\u03b1-chain-having-21-amino-acid\/\" \/>\n<meta property=\"og:site_name\" content=\"MCQ and Quiz for Exams\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-01T03:25:01+00:00\" \/>\n<meta name=\"author\" content=\"rawan239\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"rawan239\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid","description":"There are two functional insulin genes in adult humans. The gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. Both copies are typically functional, encoding the proinsulin precursor that is cleaved to form mature insulin.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-\u03b1-chain-having-21-amino-acid\/","og_locale":"en_US","og_type":"article","og_title":"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid","og_description":"There are two functional insulin genes in adult humans. The gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. Both copies are typically functional, encoding the proinsulin precursor that is cleaved to form mature insulin.","og_url":"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-\u03b1-chain-having-21-amino-acid\/","og_site_name":"MCQ and Quiz for Exams","article_published_time":"2025-06-01T03:25:01+00:00","author":"rawan239","twitter_card":"summary_large_image","twitter_misc":{"Written by":"rawan239","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-%ce%b1-chain-having-21-amino-acid\/","url":"https:\/\/exam.pscnotes.com\/mcq\/human-insulin-molecule-is-composed-of-one-%ce%b1-chain-having-21-amino-acid\/","name":"Human insulin molecule is composed of one \u03b1-chain having 21 amino acid","isPartOf":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#website"},"datePublished":"2025-06-01T03:25:01+00:00","dateModified":"2025-06-01T03:25:01+00:00","author":{"@id":"https:\/\/exam.pscnotes.com\/mcq\/#\/schema\/person\/5807dafeb27d2ec82344d6cbd6c3d209"},"description":"There are two functional insulin genes in adult humans. The gene encoding human insulin, INS, is located on chromosome 11. Humans are diploid organisms, meaning they have two sets of chromosomes (except for sex chromosomes in males). Therefore, a healthy individual has two copies of the INS gene, one on each of the homologous chromosome 11 pair. 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