Which one of the following statements is not correct?

[amp_mcq option1=”Fischer projection represents the molecule in an eclipsed conformation.” option2=”Newman projection can be presented in eclipsed, staggered and skew conformations.” option3=”Fischer projection of the molecule is its most stable conformation.” option4=”In Sawhorse projections, the lines are inclined at an angle of 120° to each other.” correct=”option3″]

This question was previously asked in

UPSC CDS-1 – 2019

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The correct option is C.

Fischer projections represent molecules in a specific orientation equivalent to an eclipsed conformation, where substituent groups on adjacent carbon atoms are aligned. Eclipsed conformations are generally higher in energy and less stable than staggered conformations due to torsional strain. The most stable conformation for a molecule is usually a staggered conformation (specifically, anti-staggered when possible), not the eclipsed conformation depicted by a Fischer projection.

Newman projections allow visualization of different conformations (eclipsed, staggered, skew) by looking down a specific bond. Sawhorse projections also depict molecules from an angle showing the relationship between groups on adjacent carbons, and the lines are often drawn to illustrate spatial arrangement, sometimes with angles around 120° to represent the tetrahedral geometry around carbon atoms in a planar projection.

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