Which one of the following examples of genetic-disorder or disease is

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Which one of the following examples of genetic-disorder or disease is due to the numerical abnormalities in the sex chromosome ?

Turner's syndrome
Down's syndrome
Haemophilia
Alkaptonuria
This question was previously asked in
UPSC Geoscientist – 2024
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A
Turner’s syndrome is a genetic disorder affecting females, caused by the complete or partial absence of one X chromosome (monosomy X, 45,XO). This is a numerical abnormality involving the sex chromosome.
Down’s syndrome is caused by trisomy of chromosome 21, an autosomal numerical abnormality. Haemophilia is an X-linked recessive disorder resulting from a mutation in a gene on the X chromosome, not a numerical abnormality of the chromosome itself. Alkaptonuria is an autosomal recessive metabolic disorder.

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