The correct answer is B. ATTRIB + r CBT.EXE.
The ATTRIB command is used to change the attributes of a file. The +r attribute makes the file read-only, which means that it cannot be modified.
The RENAME command is used to change the name of a file.
The COPY command is used to copy a file.
The MODE command is used to change the mode of a device, such as a printer or a serial port.
Therefore, the only command that will prevent subsequent changes to the file CBT.EXE is ATTRIB + r CBT.EXE.