Which cells in human body have no nucleus?

Which cells in human body have no nucleus?

Muscle cells
Phagocytic cells
Red blood cells
Ciliated cells
This question was previously asked in
UPSC CDS-1 – 2024
The correct answer is C. Red blood cells in the human body have no nucleus.
Mature mammalian red blood cells (erythrocytes) are unique among human cells in that they extrude their nucleus during development. This anucleated state, along with the absence of other organelles like mitochondria, maximizes the space available within the cell for hemoglobin, which is essential for oxygen transport.
Most other cells in the human body, including muscle cells, phagocytic cells (like white blood cells), and ciliated cells, contain a nucleus which houses the genetic material and controls cellular activities. The lack of a nucleus means that mature red blood cells cannot divide or synthesize proteins and have a limited lifespan.