Urea is produced by metabolism of

Urea is produced by metabolism of

Proteins
Carbohydrates
Lipids
Both Proteins and Carbohydrates
This question was previously asked in
UPSC CDS-2 – 2022
Urea is the main nitrogen-containing metabolic waste product in mammals. It is synthesized in the liver and excreted by the kidneys.
– Urea is produced from the breakdown of amino acids, which are the building blocks of proteins. When proteins are consumed in excess of the body’s needs or when tissues are broken down, the amino groups from amino acids are removed (deamination). These amino groups are converted into ammonia, which is toxic. The liver then converts ammonia into urea through the urea cycle.
– Carbohydrates and lipids are primarily metabolized for energy, producing carbon dioxide and water as waste products, not significant amounts of nitrogenous waste like urea.
Elevated levels of urea in the blood (azotemia or uremia) can indicate kidney dysfunction, as the kidneys are responsible for filtering urea out of the blood.
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