The room is filled . . . . . . . . smoke. A. on B. by C. to D. with

The correct answer is D. with.

The word “with” is used to indicate that something is filled with something else. In this case, the room is filled with smoke. The other options are not correct because they do not indicate that the room is filled with smoke.

• The word “on” is used to indicate that something is located on top of something else. For example, “The book is on the table.”
• The word “by” is used to indicate that something is caused by something else. For example, “The fire was caused by a spark.”
• The word “to” is used to indicate that something is going to something else. For example, “I am going to the store.”

I hope this helps!