The largest and oldest cathedral in Asia, Se Cathedral, is located in:

The correct answer is Old Goa.

Se Cathedral, also known as the Cathedral of Saint Catherine of Alexandria, is a Roman Catholic cathedral located in Old Goa, India. It is the seat of the Archdiocese of Goa and Daman. The cathedral is the largest and oldest cathedral in Asia.

The cathedral was built in the 16th century by the Portuguese. It is a large, imposing building with a Baroque style. The cathedral is made of limestone and has a large dome. The interior of the cathedral is decorated with beautiful paintings and sculptures.

The cathedral is a popular tourist destination. It is a UNESCO World Heritage Site.

The other options are incorrect.

• Panaji is the capital of Goa. It is a modern city with a population of over 100,000 people.
• Vasco da Gama is a port city in Goa. It is named after the Portuguese explorer Vasco da Gama.
• Ponda is a town in Goa. It is located about 30 kilometers from Panaji.