The headquarters of South – Central Railways is situated at

The headquarters of South Central Railways is situated at Secunderabad. It is one of the 17 railway zones of Indian Railways. It is headquartered at Secunderabad, Telangana. It covers the states of Andhra Pradesh, Telangana, Karnataka, Maharashtra, and parts of Madhya Pradesh and Chhattisgarh. The zone has a total route length of 6,162 km and a total track length of 10,278 km. It has 11 divisions, 10 workshops, and 12 training institutes. The zone operates a fleet of over 3,000 locomotives and over 10,000 coaches. It carries over 1.5 billion passengers and over 100 million tonnes of freight annually.

The other options are incorrect because:

• Mumbai (CST) is the headquarters of Central Railway.
• Chennai is the headquarters of Southern Railway.
• Mumbai (Central) is a railway station in Mumbai.