The commercial hub of Goa is:

Margao
Panaji
Vasco da Gama
Mapusa

The correct answer is Panaji. Panaji is the capital of Goa and the commercial hub of the state. It is located on the banks of the Mandovi River and is home to many government offices, businesses, and tourist attractions. Panaji is a vibrant city with a rich history and culture. It is a popular destination for both domestic and international tourists.

Margao is the second largest city in Goa and is located in the south of the state. It is a major commercial and industrial center and is home to a number of educational institutions. Margao is also a popular tourist destination, known for its beaches, churches, and temples.

Vasco da Gama is a port city located in the north of Goa. It was founded by the Portuguese in the 16th century and was named after the Portuguese explorer Vasco da Gama. Vasco da Gama is a major commercial and industrial center and is home to a number of shipyards and factories.

Mapusa is a town located in the north of Goa. It is a major commercial and trading center and is home to a number of markets and shops. Mapusa is also a popular tourist destination, known for its temples and churches.