Kidney secretes an enzyme, which changes plasma protein angiotensinoge

Kidney secretes an enzyme, which changes plasma protein angiotensinogen into angiotensin. The enzyme is

[amp_mcq option1=”Renin” option2=”Nitrogenase” option3=”Hydrolase” option4=”Mono-oxygenase” correct=”option1″]

This question was previously asked in

UPSC NDA-1 – 2017

The correct answer is Renin.

Renin is an enzyme secreted by the juxtaglomerular cells of the kidneys. It plays a crucial role in the body’s Renin-Angiotensin-Aldosterone System (RAAS), which regulates blood pressure, fluid balance, and electrolyte balance. Renin initiates the cascade by cleaving angiotensinogen, a plasma protein produced in the liver, into angiotensin I.

Angiotensin I is then converted into angiotensin II, a potent vasoconstrictor and stimulator of aldosterone secretion, by the Angiotensin-Converting Enzyme (ACE), primarily found in the lungs. The RAAS pathway is vital for maintaining homeostasis and is a target for many medications used to treat hypertension and heart failure. Nitrogenase is involved in nitrogen fixation, Hydrolase is a broad class of enzymes that catalyze hydrolysis, and Mono-oxygenase is an enzyme that incorporates one atom of molecular oxygen into a substrate. None of these are directly involved in the kidney’s conversion of angiotensinogen.

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