In the context of the developments in Bioinformatics, the term ‘transc

In the context of the developments in Bioinformatics, the term ‘transcriptome’, sometimes seen in the news, refers to

a range of enzymes used in genome editing
the full range of mRNA molecules expressed by an organism
the description of the mechanism of gene expression
a mechanism of genetic mutations taking place in cells
This question was previously asked in
UPSC IAS – 2016
In Bioinformatics, the term ‘transcriptome’ refers to the complete set of messenger RNA (mRNA) molecules expressed by an organism or in a specific cell population at a given time.
– The genome is the complete set of DNA in an organism. Genes within the genome are transcribed into messenger RNA (mRNA) molecules during the process of gene expression.
– The transcriptome represents all the mRNA transcripts present in a cell or tissue. Studying the transcriptome allows researchers to understand which genes are actively being expressed under specific conditions.
– Option A describes enzymes involved in techniques like CRISPR, which manipulate the genome.
– Option C describes the *process* of gene expression (transcription, translation), not the resulting set of mRNA molecules.
– Option D describes changes in the DNA sequence itself, which can affect the resulting transcriptome but is not what the term ‘transcriptome’ refers to.
– Transcriptomics is the study of the transcriptome and is a key area of research in molecular biology and bioinformatics, providing insights into cellular function, development, and disease.