In the context of recent advances in human reproductive technology, “Pronuclear Transfer” is used for
[amp_mcq option1=”fertilization of egg in vitro by the donor sperm” option2=”genetic modification of sperm producing cells” option3=”development of stem cells into functional embryos” option4=”prevention of mitochondrial diseases in offspring” correct=”option4″]
This question was previously asked in
UPSC IAS – 2020
Pronuclear Transfer is a technique used in assisted reproductive technology aimed at preventing the transmission of mitochondrial diseases from a mother to her child. It involves transferring the nuclear genetic material (contained in the pronuclei after fertilization) from the intended parents’ fertilized egg into a donor egg that has healthy mitochondria but has had its own nucleus removed. This creates a zygote with the intended parents’ nuclear DNA and the donor’s mitochondrial DNA, which can then be implanted.
Pronuclear Transfer is a method specifically designed to prevent the inheritance of mitochondrial diseases.