In dialysis for kidney failure patients, the dialysing fluid is iso-os

In dialysis for kidney failure patients, the dialysing fluid is iso-osmotic to

Blood
Urine
Water
Body fluid
This question was previously asked in
UPSC CISF-AC-EXE – 2018
In dialysis for kidney failure patients, the dialysing fluid is iso-osmotic to Blood.
– Dialysis is a process that filters waste products and excess fluid from the blood when the kidneys are unable to perform these functions.
– The dialysing fluid, or dialysate, is a sterile solution that is separated from the patient’s blood by a semi-permeable membrane (the dialyser or peritoneum).
– The dialysate is carefully formulated to have an osmotic pressure similar to that of normal blood plasma (making it iso-osmotic to blood) to prevent damage to blood cells and large shifts in fluid balance.
– Waste products like urea and creatinine, which are in high concentration in the patient’s blood, diffuse across the membrane into the dialysate where their concentration is low.
– Excess electrolytes in the blood can also be removed, and necessary electrolytes added to the blood from the dialysate, facilitating balance.
– Water removal (ultrafiltration) is typically achieved by creating a pressure gradient or sometimes by adding glucose to the dialysate to increase its osmotic pressure slightly compared to blood, but the base solution is iso-osmotic.
While the dialysate composition aims to restore the body’s overall fluid and electrolyte balance (related to “Body fluid”), the direct interaction is with the blood flowing through the dialyser. Therefore, its osmotic property is most critically matched to blood plasma to ensure safe and effective filtration and solute exchange without causing harm to blood cells.
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