In a mammalian cell, the protein is synthesized by

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Ribosome.

Golgi.

Lysosome.

Smooth endoplasmic reticulum.

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UPSC CISF-AC-EXE – 2021

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Ribosomes are small organelles found in the cytoplasm of all cells (prokaryotic and eukaryotic), as well as attached to the endoplasmic reticulum in eukaryotic cells. They are the cellular machinery responsible for protein synthesis, a process called translation, where messenger RNA (mRNA) is decoded to build a protein chain.

Protein synthesis involves two main steps: transcription (DNA to mRNA) and translation (mRNA to protein). Translation occurs on ribosomes. Ribosomes are composed of ribosomal RNA (rRNA) and proteins and consist of two subunits, a large one and a small one, which come together during translation.

The Golgi apparatus modifies, sorts, and packages proteins and lipids for secretion or delivery to other organelles. Lysosomes contain hydrolytic enzymes for digesting waste materials and cellular debris. The smooth endoplasmic reticulum is involved in lipid synthesis, detoxification, and calcium storage, but not protein synthesis (which occurs on rough ER due to attached ribosomes, or free in the cytoplasm).

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