The correct answer is: A. 400 BC
Hippocrates was a Greek physician of the Classical period who is considered one of the most outstanding figures in the history of medicine. He is often referred to as the “Father of Medicine” in recognition of his lasting contributions to the field as the founder of the Hippocratic School of Medicine. This medical school revolutionized medicine in ancient Greece, establishing it as a discipline distinct from other arts. Through the work of his many disciples, the Hippocratic tradition of medicine spread throughout the ancient world and became the basis of Western medicine.
Hippocrates is also credited with being the first to mention air pollution in his writings. In his book “On Airs, Waters, and Places,” he discusses the effects of air pollution on human health. He notes that air pollution can cause a variety of health problems, including respiratory problems, skin problems, and even death.
The other options are incorrect because they are not the years in which Hippocrates mentioned air pollution. Option B, 500 BC, is the year in which Hippocrates is believed to have been born. Option C, 620 BC, is the year in which Hippocrates is believed to have died. Option D, 354 BC, is the year in which Aristotle was born.
In conclusion, the correct answer to the question “Hippocrates mentioned air pollution in ____ BC” is: A. 400 BC