Genuine :

Unnatural
Synthetic
Artificial
Sham

The correct answer is A. Genuine.

Genuine means real, authentic, or true. It is the opposite of fake or counterfeit.

Unnatural means not occurring in nature or not according to nature. It is the opposite of natural.

Synthetic means made by humans or by a process that does not occur in nature. It is the opposite of natural.

Artificial means made by humans or by a process that does not occur in nature. It is the opposite of natural.

Sham means not genuine or real; false. It is the opposite of genuine.