The answer is B. MYGHZ.
In each of the other options, the letters are in alphabetical order. For example, in A. VYAKB, the letters are V, Y, A, K, and B, which are in alphabetical order. In C. LMVOX, the letters are L, M, V, O, and X, which are in alphabetical order. In D. FJNRV, the letters are F, J, N, R, and V, which are in alphabetical order. In E. QBSPN, the letters are Q, B, S, P, and N, which are in alphabetical order.
However, in B. MYGHZ, the letters are M, Y, G, H, and Z, which are not in alphabetical order.