Consider the following pairs of vaccine and category/type: 1. Covax

Consider the following pairs of vaccine and category/type:

  • 1. Covaxin : Inactivated pathogen-based vaccine
  • 2. Covishield : mRNA vaccine
  • 3. Sputnik V : Viral vector-based vaccine

Which of the pairs given above is/are correctly matched ?

1 only
2 and 3 only
1 and 3 only
1, 2 and 3
This question was previously asked in
UPSC CDS-1 – 2022
Pairs 1 and 3 are correctly matched regarding the vaccine type, while pair 2 is incorrect.
– Covaxin, developed by Bharat Biotech in India, is an inactivated vaccine. It uses a killed version of the SARS-CoV-2 virus to trigger an immune response.
– Covishield, manufactured by Serum Institute of India, is a viral vector vaccine. It uses a modified adenovirus (a common cold virus) to deliver genetic material of the SARS-CoV-2 spike protein into cells, prompting an immune response. It is not an mRNA vaccine.
– Sputnik V, developed by the Gamaleya Research Institute in Russia, is also a viral vector vaccine, using two different adenoviruses (Ad26 and Ad5) for the two doses.
– mRNA vaccines (like Pfizer-BioNTech and Moderna) use messenger RNA to instruct cells to make a piece of the virus’s spike protein, triggering an immune response.
– Viral vector vaccines (like AstraZeneca/Covishield, Sputnik V, and Johnson & Johnson) use a harmless virus to deliver genetic instructions for making the spike protein.
– Inactivated vaccines (like Covaxin, Sinovac, Sinopharm) use killed viral particles.
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