Antonym of GAINSAY

affirm
reject
appreciate
lose

The correct answer is B. reject.

To gainsay is to contradict or deny something. The opposite of gainsay is to affirm or agree with something.

A. affirm means to state something positively or to declare something to be true.
B. reject means to refuse to accept or to consider something.
C. appreciate means to value or to be grateful for something.
D. lose means to no longer have or to be deprived of something.

In this case, the best answer is B. reject. This is because gainsay means to contradict or deny something, and the opposite of contradict or deny is to affirm or agree with something.