The term 'ACE2' is talked about in the context of

The term ‘ACE2’ is talked about in the context of

[amp_mcq option1=”genes introduced in the genetically modified plants” option2=”development of India’s own satellite navigation system” option3=”radio collars for wildlife tracking” option4=”spread of viral diseases” correct=”option4″]

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UPSC IAS – 2021

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The term ‘ACE2’ stands for Angiotensin-converting enzyme 2. This enzyme is a protein found on the surface of many cells, particularly in the lungs, heart, kidneys, and intestines. It became widely known because it serves as the primary receptor that the SARS-CoV-2 virus (which causes COVID-19) uses to enter human cells. Therefore, ACE2 is talked about extensively in the context of the spread of viral diseases, specifically COVID-19.

– ACE2 is a protein enzyme found on cell surfaces.
– It acts as a receptor for coronaviruses, including SARS-CoV-2.
– The binding of the virus to ACE2 is the initial step in cellular infection.

ACE2 is part of the renin-angiotensin system (RAS), which plays a crucial role in regulating blood pressure and fluid balance. Research is ongoing to understand the complex interaction between SARS-CoV-2 and ACE2, and how it affects the RAS and contributes to the severity of COVID-19 disease.

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