Which one of the following hormones is essential for the uptake of glu

Which one of the following hormones is essential for the uptake of glucose by cells in the human body?

GH
TSH
Insulin
Cortisol
This question was previously asked in
UPSC CDS-2 – 2016
Insulin is the hormone essential for the uptake of glucose by cells in the human body.
– Insulin is a hormone produced by the beta cells of the pancreas.
– Its primary role is to regulate blood glucose levels by facilitating the uptake of glucose from the bloodstream into most cells of the body, particularly muscle, fat, and liver cells.
– Insulin binds to receptors on cell membranes, triggering the translocation of glucose transporters (like GLUT4) to the cell surface, allowing glucose to enter the cell.
– GH (Growth Hormone) has effects on metabolism, including promoting growth and cell reproduction. It can increase blood glucose levels by stimulating gluconeogenesis and inhibiting glucose uptake.
– TSH (Thyroid Stimulating Hormone) stimulates the thyroid gland to produce thyroid hormones, which regulate metabolism but are not directly involved in glucose uptake by most cells.
– Cortisol is a glucocorticoid hormone produced by the adrenal glands. It also influences glucose metabolism, typically by increasing blood glucose levels (gluconeogenesis) and reducing peripheral glucose uptake.
Diabetes mellitus is a disease characterized by high blood glucose levels resulting from either insufficient insulin production (Type 1) or the body’s cells not responding properly to insulin (Type 2).