Tamil Nadu is famous for the cultivation of this flower:

Jasmine
Marigold
Rose
Lotus

The correct answer is: Jasmine.

Jasmine is a genus of flowering plants in the olive family Oleaceae. It is native to tropical and warm temperate regions of the Old World, from Africa to Australia. Jasmine is a popular ornamental plant, and its flowers are used in perfumery.

Marigold is a genus of annual and perennial plants in the daisy family Asteraceae. It is native to the Americas, but has been widely introduced to other parts of the world. Marigolds are popular garden flowers, and are also used in some traditional medicines.

Rose is a genus of flowering plants in the rose family Rosaceae. It is native to Asia, Europe, North America, and Northwestern Africa. Roses are one of the most popular garden flowers, and are also used in perfumery and cosmetics.

Lotus is a genus of aquatic plants in the lily family Nelumbonaceae. It is native to tropical and subtropical regions of Asia, Africa, and Australia. Lotuses are sacred in Hinduism and Buddhism, and are also used in traditional medicine.

In Tamil Nadu, jasmine is the most popular flower. It is grown in many parts of the state, and is used in a variety of products, including perfumes, cosmetics, and garlands. Jasmine is also used in traditional medicine, and is believed to have a number of health benefits.