Who holds second and third place for most yards rushing in a single season in the NFL?

Barry Sanders
Jim Brown
OJ Simpson
Dick Lane

The correct answer is: A. Barry Sanders and B. Jim Brown.

Barry Sanders holds the second place for most yards rushing in a single season in the NFL with 2,115 yards in 1997. Jim Brown holds the third place with 1,863 yards in 1963.

OJ Simpson holds the first place with 2,003 yards in 1973. Dick Lane was a cornerback who played for the Chicago Cardinals and the Los Angeles Rams from 1952 to 1965. He is not a running back and did not rush for any yards in a single season.