The correct answer is A. unsafe.
An unsafe reputation means that someone is not to be trusted and could potentially harm you. This could be due to their criminal history, violent tendencies, or simply their reckless behavior. It is important to avoid people with an unsafe reputation, as they could pose a serious danger to your safety.
The other options are not as dangerous as unsafe. Unsavory means unpleasant or distasteful, but it does not necessarily mean that someone is dangerous. Unsteady means not reliable or trustworthy, but it does not necessarily mean that someone is violent. Unsanctified means not holy or sacred, but it does not necessarily mean that someone is dangerous.
It is important to be aware of the reputation of the people you associate with, as it can have a significant impact on your own safety. If you know someone has an unsafe reputation, it is best to avoid them altogether.