As the news of the natural . . . . . . . . spread offers of relief poured in.

misery
misfortune
calamity
collapse

The correct answer is: C. calamity.

A calamity is a great and sudden misfortune, especially one causing widespread distress or destruction.

The other options are:

  • Misery: great unhappiness or suffering.
  • Misfortune: an unlucky event or turn of events.
  • Collapse: the act of falling down or failing to continue.

In the context of the question, the news of the natural calamity spread offers of relief poured in. This suggests that the calamity was a great and sudden misfortune, especially one causing widespread distress or destruction. The other options do not fit as well in the context of the question.