The correct answer is C. interrupt.
To interrupt is to stop someone in the middle of what they are saying. It can be done by speaking over them, making noise, or doing something else that draws attention away from them. Interrupting can be rude and disrespectful, and it can make it difficult for the person who is being interrupted to get their point across.
The other options are not as accurate as interrupt. Disrupt means to disturb or interfere with something, but it does not necessarily mean to stop someone in the middle of what they are saying. Interface means to connect or interact with something, but it does not necessarily mean to interrupt someone. Disturb means to make someone feel uneasy or uncomfortable, but it does not necessarily mean to stop someone in the middle of what they are saying.