The lease of our premises has ……… and we have to vacate it.

run out
run off
run over
run down

The correct answer is A. The lease of our premises has run out and we have to vacate it.

To run out means to come to an end. In this case, the lease of the premises has come to an end, so the tenants must leave.

The other options are incorrect. To run off means to move away quickly. To run over means to hit and injure someone or something with a vehicle. To run down means to make someone or something weak or tired.