He does not seem . . . . . . . . be a criminal. A. with B. from C. on D. to

The correct answer is: to.

The word “to” is used to indicate a purpose or intention. In this case, the speaker is saying that the person does not seem to have the intention of being a criminal.

The other options are incorrect because they do not make sense in the context of the sentence.

• With is used to indicate association or connection. In this case, the speaker is not saying that the person is associated with criminals.
• From is used to indicate origin or source. In this case, the speaker is not saying that the person comes from a criminal background.
• On is used to indicate location or position. In this case, the speaker is not saying that the person is located in a criminal environment.

Therefore, the correct answer is to.