{"id":16026,"date":"2025-04-26T01:03:28","date_gmt":"2025-04-26T01:03:28","guid":{"rendered":"https:\/\/exam.pscnotes.com\/current-affairs\/?p=16026"},"modified":"2025-04-26T01:03:54","modified_gmt":"2025-04-26T01:03:54","slug":"haemophilia-gene-therapy-trial","status":"publish","type":"post","link":"https:\/\/exam.pscnotes.com\/current-affairs\/haemophilia-gene-therapy-trial\/","title":{"rendered":"Haemophilia Gene Therapy Trial"},"content":{"rendered":"<ul>\n<li><strong>India&#8217;s First Gene Therapy Trial for Haemophilia:<\/strong> BRIC-inStem, Bengaluru, in collaboration with CMC Vellore, successfully conducted India\u2019s first-in-human gene therapy trial for Haemophilia.<\/li>\n<li><strong>Gene Therapy Basics:<\/strong> Gene therapy modifies or replaces faulty genes to treat or prevent diseases, addressing the root genetic cause instead of just symptoms. It involves replacing, inactivating, or introducing new genes.<\/li>\n<li><strong>Haemophilia Explained:<\/strong> Haemophilia is a genetic bleeding disorder due to mutations in genes encoding clotting proteins, primarily affecting males.<\/li>\n<li><strong>BRIC-inStem&#8217;s Role:<\/strong> BRIC-inStem integrates 14 research institutions and pioneers translational research, including gene therapy. They also developed solutions like anti-viral masks and pesticide shields.<\/li>\n<li><strong>Minister&#8217;s Commendation:<\/strong> Dr. Jitendra Singh hailed the gene therapy trial as a milestone and emphasized biotechnology&#8217;s role in nation-building and the future economy.<\/li>\n<li><strong>Biotech Sector Growth:<\/strong> India&#8217;s biotechnology sector has grown significantly, with a vision to reach $300 billion by 2030, supported by policy reforms like the BIO-E3 Policy.<\/li>\n<li><strong>Startup Ecosystem:<\/strong> The number of biotech startups has increased dramatically, highlighting the sector&#8217;s dynamism.<\/li>\n<li><strong>Biosafety Lab:<\/strong> BRIC-inStem&#8217;s Biosafety Level III lab is crucial for studying high-risk pathogens under the One Health Mission, enhancing pandemic preparedness.<\/li>\n<li><strong>Focus on Birth Defects:<\/strong> The newly launched CReATE addresses birth defects and infertility through developmental biology research.<\/li>\n<li><strong>Call for Collaboration:<\/strong> Dr. Singh urged greater collaboration between scientific and medical institutions.<\/li>\n<li><strong>Bio-Driven Economy:<\/strong> India&#8217;s future economy will be bio-driven, with institutions like BRIC-inStem leading the transformation.<\/li>\n<li><strong>Gene therapy in Haemophilia<\/strong> Gene therapy in Haemophilia involves delivering a functional copy of the faulty gene to the patient\u2019s liver cells to enable the production of clotting factors.<\/li>\n<li><strong>Clotting factor<\/strong> Factor VIII is deficient in Haemophilia A, while Factor IX is deficient in Haemophilia B.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>India&#8217;s First Gene Therapy Trial for Haemophilia: BRIC-inStem, Bengaluru, in collaboration with CMC Vellore, successfully conducted India\u2019s first-in-human gene therapy trial for Haemophilia. Gene Therapy Basics: Gene therapy modifies or replaces faulty genes to treat or prevent diseases, addressing the root genetic cause instead of just symptoms. It involves replacing, inactivating, or introducing new genes. &#8230; <a title=\"Haemophilia Gene Therapy Trial\" class=\"read-more\" href=\"https:\/\/exam.pscnotes.com\/current-affairs\/haemophilia-gene-therapy-trial\/\" aria-label=\"Read more about Haemophilia Gene Therapy Trial\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":16033,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[595],"tags":[1285],"class_list":["post-16026","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-current-affairs","tag-25-04-25"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.2 (Yoast SEO v23.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Haemophilia Gene Therapy Trial - Current Affairs Exam<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/exam.pscnotes.com\/current-affairs\/haemophilia-gene-therapy-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Haemophilia Gene Therapy Trial\" \/>\n<meta property=\"og:description\" content=\"India&#8217;s First Gene Therapy Trial for Haemophilia: BRIC-inStem, Bengaluru, in collaboration with CMC Vellore, successfully conducted India\u2019s first-in-human gene therapy trial for Haemophilia. 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Gene Therapy Basics: Gene therapy modifies or replaces faulty genes to treat or prevent diseases, addressing the root genetic cause instead of just symptoms. It involves replacing, inactivating, or introducing new genes. ... 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