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Project Overview: The Genome India Project (GIP) is mapping the genetic diversity of the Indian population, with the first phase completed, cataloging the complete gene sequences of
10,000 individuals from 83 population groups. -
Significance for Healthcare: The project aims to enable early detection of disease susceptibility (diabetes, cancers, rare disorders) and facilitate personalized medicine tailored to an individual’s genetic makeup. It can also help develop population-specific drugs and improve diagnostics.
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Public Health & Policy: GIP data will assist in epidemiological planning and targeted interventions for specific regions or communities, particularly for rare diseases unique to certain Indian sub-populations.
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Population Genomics & Anthropology: The project aids in tracing ancestry, migrations, evolutionary history of various Indian communities, and understanding genetic adaptations to the local climate and environment.
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Evolutionary Insights: The database will reveal information about the evolutionary history, how populations migrated, socialized, intermingled, and adapted to local conditions.
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Scientific and Strategic Importance: The project positions India as a leader in genomic science, establishing self-reliance in genomic databases and opening opportunities in biotech, pharma, AI-based genomics, and medical research.
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Germline Sequences and Personalized Medicine: The database will store germline sequences to analyze predisposition to diseases and treatment effectiveness. This information is vital in the evolution of personalized medicine where a patient gets a tailor-made solution for a specific disease.
15.04.25
C. Sankaran Nair
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Historical Context: Prime Minister Modi criticized the Congress for neglecting Chettur Sankaran Nair’s legacy.
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Upcoming Film: A film, “Kesari Chapter 2”, based on the book “The Case That Shook the Empire,” is in production, highlighting Nair’s life.
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Key Figure: Chettur Sankaran Nair was a prominent Indian jurist, statesman, and nationalist leader during British rule.
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Early Life and Career: Born in 1857
in Kerala, he graduated in law and served as a judge, advocating for social reforms. -
President of INC: He became the youngest president of the Indian National
Congress in 1897. -
Viceroy’s Executive Council: Served as the sole Indian member, advocating for constitutional reforms.
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Jallianwala Bagh Protest: Resigned from the Viceroy’s Council in 1919 to protest the Jallianwala Bagh Massacre. This was a bold move against the British.
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Book and Defamation: Authored “Gandhi and Anarchy,” criticizing both Gandhi and British policies. Sued by Michael O’Dwyer for defamation.
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O’Dwyer v. Nair Trial: Lost the defamation case in London but refused to apologize, highlighting his unwavering principles and the biases of the British system.
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Legacy: Nair’s actions, especially his resignation and defiance in the trial, amplified nationalist sentiments against the British.
Kuno to Gandhi Sagar
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Relocation Approved: The Cheetah Project Steering Committee has approved relocating some cheetahs from Kuno National Park (KNP) to Gandhi Sagar Wildlife Sanctuary (GSWS) in Madhya Pradesh.
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Project Goal: The move aims to establish a cheetah meta-population of 60-70 individuals across the Kuno-Gandhi Sagar landscape spanning Madhya Pradesh and Rajasthan.
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GSWS Preparation: The Madhya Pradesh forest department has been preparing GSWS for over a year for cheetah introduction.
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Initial Phase: The plan is to release 4-5 cheetahs into a fenced 64 sq km area in the western part of GSWS after removing leopards to prevent conflict.
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Source of Cheetahs: It is yet to be decided whether the cheetahs relocated will be from the wild or enclosures within Kuno. As of now there are 26 cheetahs in Kuno, 17 are in wild and 9 in enclosures
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Prey Augmentation: Concerns about prey availability at Gandhi Sagar are being addressed by introducing chital from other forests and maintaining herbivore enclosures for in-situ breeding. Current prey includes chinkara, chousingha, nilgai and chital.
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Project Setbacks: Project Cheetah has faced setbacks, including the deaths of 8 adult cheetahs and 5 cubs at Kuno.
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Committee Concerns: The committee expressed displeasure over a video of a forest department driver offering water to a cheetah and cubs, emphasizing the need for better training and adherence to SOPs. They also
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Cheetah Introduction Rationale: Cheetahs were reintroduced to India to restore ecological balance and re-establish their role as apex predators.